Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle
The peroxisome proliferator-activated receptor gamma (PPARγ) gene plays an important role in the biosynthesis process controlled by a number of fatty acid transcription factors. This study investigates the relationships between 130 single-nucleotide polymorphisms (SNPs) in the PPARγ gene and the fat...
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Asian-Australasian Association of Animal Production Societies
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doaj-21c13a5888294cd8b2fdbaa92bd5a99d2020-11-25T01:30:46ZengAsian-Australasian Association of Animal Production SocietiesAsian-Australasian Journal of Animal Sciences1011-23671976-55172016-02-0129218419410.5713/ajas.15.050223350Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native CattleJea-young LeeJae-jung Ha0Yong-soo Park1Jun-koo Yi2Seunguk Lee3Seyoung Mun4Kyudong Han5J.-J. Kim6Hyun-Ji KimDong-yep Oh7 Livestock Research institute, Yeongju 750-871, .Korea Department of Equine Industry, Korea National College of Agriculture and Fisheries, Hwaseong 445-760, .Korea Livestock Research institute, Yeongju 750-871, .Korea Biotechnology Research Center, The University of Tokyo, Bunkyo 113-8657, .Tokyo Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 330-714, .Korea Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 330-714, .Korea School of Biotechnology, Yeungnam University, Gyeongsan 712-749, .Korea Livestock Research institute, Yeongju 750-871, .KoreaThe peroxisome proliferator-activated receptor gamma (PPARγ) gene plays an important role in the biosynthesis process controlled by a number of fatty acid transcription factors. This study investigates the relationships between 130 single-nucleotide polymorphisms (SNPs) in the PPARγ gene and the fatty acid composition of muscle fat in the commercial population of Korean native cattle. We identified 38 SNPs and verified relationships between 3 SNPs (g.1159-71208 A>G, g.42555-29812 G>A, and g.72362 G>T) and the fatty acid composition of commercial Korean native cattle (n = 513). Cattle with the AA genotype of g.1159-71208 A>G and the GG genotype of g.42555-29812 G>A and g.72362 G>T had higher levels of monounsaturated fatty acids and carcass traits (p<0.05). The results revealed that the 3 identified SNPs in the PPARγ gene affected fatty acid composition and carcass traits, suggesting that these 3 SNPs may improve the flavor and quality of beef in commercial Korean native cattle.http://www.ajas.info/upload/pdf/ajas-29-2-184.pdfKorean Native CattleSNPFatty Acid CompositionMarbling Score |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jea-young Lee Jae-jung Ha Yong-soo Park Jun-koo Yi Seunguk Lee Seyoung Mun Kyudong Han J.-J. Kim Hyun-Ji Kim Dong-yep Oh |
spellingShingle |
Jea-young Lee Jae-jung Ha Yong-soo Park Jun-koo Yi Seunguk Lee Seyoung Mun Kyudong Han J.-J. Kim Hyun-Ji Kim Dong-yep Oh Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle Asian-Australasian Journal of Animal Sciences Korean Native Cattle SNP Fatty Acid Composition Marbling Score |
author_facet |
Jea-young Lee Jae-jung Ha Yong-soo Park Jun-koo Yi Seunguk Lee Seyoung Mun Kyudong Han J.-J. Kim Hyun-Ji Kim Dong-yep Oh |
author_sort |
Jea-young Lee |
title |
Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle |
title_short |
Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle |
title_full |
Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle |
title_fullStr |
Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle |
title_full_unstemmed |
Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle |
title_sort |
relationship between single nucleotide polymorphisms in the peroxisome proliferator-activated receptor gamma gene and fatty acid composition in korean native cattle |
publisher |
Asian-Australasian Association of Animal Production Societies |
series |
Asian-Australasian Journal of Animal Sciences |
issn |
1011-2367 1976-5517 |
publishDate |
2016-02-01 |
description |
The peroxisome proliferator-activated receptor gamma (PPARγ) gene plays an important role in the biosynthesis process controlled by a number of fatty acid transcription factors. This study investigates the relationships between 130 single-nucleotide polymorphisms (SNPs) in the PPARγ gene and the fatty acid composition of muscle fat in the commercial population of Korean native cattle. We identified 38 SNPs and verified relationships between 3 SNPs (g.1159-71208 A>G, g.42555-29812 G>A, and g.72362 G>T) and the fatty acid composition of commercial Korean native cattle (n = 513). Cattle with the AA genotype of g.1159-71208 A>G and the GG genotype of g.42555-29812 G>A and g.72362 G>T had higher levels of monounsaturated fatty acids and carcass traits (p<0.05). The results revealed that the 3 identified SNPs in the PPARγ gene affected fatty acid composition and carcass traits, suggesting that these 3 SNPs may improve the flavor and quality of beef in commercial Korean native cattle. |
topic |
Korean Native Cattle SNP Fatty Acid Composition Marbling Score |
url |
http://www.ajas.info/upload/pdf/ajas-29-2-184.pdf |
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