Immunomodulation of Nanoparticles in Nanomedicine Applications
Nanoparticles (NPs) have promising applications in medicine. Immune system is an important protective system to defend organisms from non-self matters. NPs interact with the immune system and modulate its function, leading to immunosuppression or immunostimulation. These modulating effects may bring...
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2014-01-01
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Online Access: | http://dx.doi.org/10.1155/2014/426028 |
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doaj-21d219d7917047bc9bcf7ac2febe705f2020-11-24T21:58:16ZengHindawi LimitedBioMed Research International2314-61332314-61412014-01-01201410.1155/2014/426028426028Immunomodulation of Nanoparticles in Nanomedicine ApplicationsQing Jiao0Liwen Li1Qingxin Mu2Qiu Zhang3School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, ChinaSchool of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, ChinaClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USASchool of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, ChinaNanoparticles (NPs) have promising applications in medicine. Immune system is an important protective system to defend organisms from non-self matters. NPs interact with the immune system and modulate its function, leading to immunosuppression or immunostimulation. These modulating effects may bring benefits or danger. Compositions, sizes, and surface chemistry, and so forth, affect these immunomodulations. Here we give an overview of the relationship between the physicochemical properties of NPs, which are candidates to be applied in medicine, and their immunomodulation properties.http://dx.doi.org/10.1155/2014/426028 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Qing Jiao Liwen Li Qingxin Mu Qiu Zhang |
spellingShingle |
Qing Jiao Liwen Li Qingxin Mu Qiu Zhang Immunomodulation of Nanoparticles in Nanomedicine Applications BioMed Research International |
author_facet |
Qing Jiao Liwen Li Qingxin Mu Qiu Zhang |
author_sort |
Qing Jiao |
title |
Immunomodulation of Nanoparticles in Nanomedicine Applications |
title_short |
Immunomodulation of Nanoparticles in Nanomedicine Applications |
title_full |
Immunomodulation of Nanoparticles in Nanomedicine Applications |
title_fullStr |
Immunomodulation of Nanoparticles in Nanomedicine Applications |
title_full_unstemmed |
Immunomodulation of Nanoparticles in Nanomedicine Applications |
title_sort |
immunomodulation of nanoparticles in nanomedicine applications |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2014-01-01 |
description |
Nanoparticles (NPs) have promising applications in medicine. Immune system is an important protective system to defend organisms from non-self matters. NPs interact with the immune system and modulate its function, leading to immunosuppression or immunostimulation. These modulating effects may bring benefits or danger. Compositions, sizes, and surface chemistry, and so forth, affect these immunomodulations. Here we give an overview of the relationship between the physicochemical properties of NPs, which are candidates to be applied in medicine, and their immunomodulation properties. |
url |
http://dx.doi.org/10.1155/2014/426028 |
work_keys_str_mv |
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_version_ |
1725852637033660416 |