Immunomodulation of Nanoparticles in Nanomedicine Applications

Immunomodulation of Nanoparticles in Nanomedicine Applications

Nanoparticles (NPs) have promising applications in medicine. Immune system is an important protective system to defend organisms from non-self matters. NPs interact with the immune system and modulate its function, leading to immunosuppression or immunostimulation. These modulating effects may bring...

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Main Authors: Qing Jiao, Liwen Li, Qingxin Mu, Qiu Zhang
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/426028
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spelling doaj-21d219d7917047bc9bcf7ac2febe705f2020-11-24T21:58:16ZengHindawi LimitedBioMed Research International2314-61332314-61412014-01-01201410.1155/2014/426028426028Immunomodulation of Nanoparticles in Nanomedicine ApplicationsQing Jiao0Liwen Li1Qingxin Mu2Qiu Zhang3School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, ChinaSchool of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, ChinaClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USASchool of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, ChinaNanoparticles (NPs) have promising applications in medicine. Immune system is an important protective system to defend organisms from non-self matters. NPs interact with the immune system and modulate its function, leading to immunosuppression or immunostimulation. These modulating effects may bring benefits or danger. Compositions, sizes, and surface chemistry, and so forth, affect these immunomodulations. Here we give an overview of the relationship between the physicochemical properties of NPs, which are candidates to be applied in medicine, and their immunomodulation properties.http://dx.doi.org/10.1155/2014/426028
collection DOAJ
language English
format Article
sources DOAJ
author Qing Jiao
Liwen Li
Qingxin Mu
Qiu Zhang
spellingShingle Qing Jiao
Liwen Li
Qingxin Mu
Qiu Zhang
Immunomodulation of Nanoparticles in Nanomedicine Applications
BioMed Research International
author_facet Qing Jiao
Liwen Li
Qingxin Mu
Qiu Zhang
author_sort Qing Jiao
title Immunomodulation of Nanoparticles in Nanomedicine Applications
title_short Immunomodulation of Nanoparticles in Nanomedicine Applications
title_full Immunomodulation of Nanoparticles in Nanomedicine Applications
title_fullStr Immunomodulation of Nanoparticles in Nanomedicine Applications
title_full_unstemmed Immunomodulation of Nanoparticles in Nanomedicine Applications
title_sort immunomodulation of nanoparticles in nanomedicine applications
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2014-01-01
description Nanoparticles (NPs) have promising applications in medicine. Immune system is an important protective system to defend organisms from non-self matters. NPs interact with the immune system and modulate its function, leading to immunosuppression or immunostimulation. These modulating effects may bring benefits or danger. Compositions, sizes, and surface chemistry, and so forth, affect these immunomodulations. Here we give an overview of the relationship between the physicochemical properties of NPs, which are candidates to be applied in medicine, and their immunomodulation properties.
url http://dx.doi.org/10.1155/2014/426028
work_keys_str_mv AT qingjiao immunomodulationofnanoparticlesinnanomedicineapplications
AT liwenli immunomodulationofnanoparticlesinnanomedicineapplications
AT qingxinmu immunomodulationofnanoparticlesinnanomedicineapplications
AT qiuzhang immunomodulationofnanoparticlesinnanomedicineapplications
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