World’s First Clinical Case of Gene-Activated Bone Substitute Application

Treatment of patients with large bone defects is a complex clinical problem. We have initiated the first clinical study of a gene-activated bone substitute composed of the collagen-hydroxyapatite scaffold and plasmid DNA encoding vascular endothelial growth factor. The first patient with two nonunio...

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Bibliographic Details
Main Authors: I. Y. Bozo, R. V. Deev, A. Y. Drobyshev, A. A. Isaev, I. I. Eremin
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2016/8648949