Chromosome Translocations as a Driver of Diversification in Mole Voles <i>Ellobius</i> (Rodentia, Mammalia)
The involvement of chromosome changes in the initial steps of speciation is controversial. Here we examine diversification trends within the mole voles <i>Ellobius</i>, a group of subterranean rodents. The first description of their chromosome variability was published almost 40 years ag...
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doaj-21dd4986af8d4689b47945e36cef1b8e2020-11-25T02:48:02ZengMDPI AGInternational Journal of Molecular Sciences1422-00672019-09-012018446610.3390/ijms20184466ijms20184466Chromosome Translocations as a Driver of Diversification in Mole Voles <i>Ellobius</i> (Rodentia, Mammalia)Svetlana A. Romanenko0Elena A. Lyapunova1Abdusattor S. Saidov2Patricia C.M. O’Brien3Natalia A. Serdyukova4Malcolm A. Ferguson-Smith5Alexander S. Graphodatsky6Irina Bakloushinskaya7Institute of Molecular and Cellular Biology, Siberian Branch, Russian Academy of Sciences, 630090 Novosibirsk, RussiaKoltzov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, RussiaInstitute of Zoology and Parasitology, Academy of Sciences of Tajikistan, Dushanbe 734025, TajikistanCambridge Resource Centre for Comparative Genomics, Department of Veterinary Medicine, University of Cambridge, Cambridge, CB3 0ES, UKInstitute of Molecular and Cellular Biology, Siberian Branch, Russian Academy of Sciences, 630090 Novosibirsk, RussiaCambridge Resource Centre for Comparative Genomics, Department of Veterinary Medicine, University of Cambridge, Cambridge, CB3 0ES, UKInstitute of Molecular and Cellular Biology, Siberian Branch, Russian Academy of Sciences, 630090 Novosibirsk, RussiaKoltzov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, RussiaThe involvement of chromosome changes in the initial steps of speciation is controversial. Here we examine diversification trends within the mole voles <i>Ellobius</i>, a group of subterranean rodents. The first description of their chromosome variability was published almost 40 years ago. Studying the G-band structure of chromosomes in numerous individuals revealed subsequent homologous, step-by-step, Robertsonian translocations, which changed diploid numbers from 54 to 30. Here we used a molecular cytogenetic strategy which demonstrates that chromosomal translocations are not always homologous; consequently, karyotypes with the same diploid number can carry different combinations of metacentrics. We further showed that at least three chromosomal forms with 2n = 34 and distinct metacentrics inhabit the Pamir-Alay mountains. Each of these forms independently hybridized with <i>E. tancrei</i>, 2n = 54, forming separate hybrid zones. The chromosomal variations correlate slightly with geographic barriers. Additionally, we confirmed that the emergence of partial or monobrachial homology appeared to be a strong barrier for hybridization in nature, in contradistinction to experiments which we reported earlier. We discuss the possibility of whole arm reciprocal translocations for mole voles. Our findings suggest that chromosomal translocations lead to diversification and speciation.https://www.mdpi.com/1422-0067/20/18/4466chromosome paintingkaryotypemole volespeciationsubterranean rodents |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Svetlana A. Romanenko Elena A. Lyapunova Abdusattor S. Saidov Patricia C.M. O’Brien Natalia A. Serdyukova Malcolm A. Ferguson-Smith Alexander S. Graphodatsky Irina Bakloushinskaya |
spellingShingle |
Svetlana A. Romanenko Elena A. Lyapunova Abdusattor S. Saidov Patricia C.M. O’Brien Natalia A. Serdyukova Malcolm A. Ferguson-Smith Alexander S. Graphodatsky Irina Bakloushinskaya Chromosome Translocations as a Driver of Diversification in Mole Voles <i>Ellobius</i> (Rodentia, Mammalia) International Journal of Molecular Sciences chromosome painting karyotype mole vole speciation subterranean rodents |
author_facet |
Svetlana A. Romanenko Elena A. Lyapunova Abdusattor S. Saidov Patricia C.M. O’Brien Natalia A. Serdyukova Malcolm A. Ferguson-Smith Alexander S. Graphodatsky Irina Bakloushinskaya |
author_sort |
Svetlana A. Romanenko |
title |
Chromosome Translocations as a Driver of Diversification in Mole Voles <i>Ellobius</i> (Rodentia, Mammalia) |
title_short |
Chromosome Translocations as a Driver of Diversification in Mole Voles <i>Ellobius</i> (Rodentia, Mammalia) |
title_full |
Chromosome Translocations as a Driver of Diversification in Mole Voles <i>Ellobius</i> (Rodentia, Mammalia) |
title_fullStr |
Chromosome Translocations as a Driver of Diversification in Mole Voles <i>Ellobius</i> (Rodentia, Mammalia) |
title_full_unstemmed |
Chromosome Translocations as a Driver of Diversification in Mole Voles <i>Ellobius</i> (Rodentia, Mammalia) |
title_sort |
chromosome translocations as a driver of diversification in mole voles <i>ellobius</i> (rodentia, mammalia) |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1422-0067 |
publishDate |
2019-09-01 |
description |
The involvement of chromosome changes in the initial steps of speciation is controversial. Here we examine diversification trends within the mole voles <i>Ellobius</i>, a group of subterranean rodents. The first description of their chromosome variability was published almost 40 years ago. Studying the G-band structure of chromosomes in numerous individuals revealed subsequent homologous, step-by-step, Robertsonian translocations, which changed diploid numbers from 54 to 30. Here we used a molecular cytogenetic strategy which demonstrates that chromosomal translocations are not always homologous; consequently, karyotypes with the same diploid number can carry different combinations of metacentrics. We further showed that at least three chromosomal forms with 2n = 34 and distinct metacentrics inhabit the Pamir-Alay mountains. Each of these forms independently hybridized with <i>E. tancrei</i>, 2n = 54, forming separate hybrid zones. The chromosomal variations correlate slightly with geographic barriers. Additionally, we confirmed that the emergence of partial or monobrachial homology appeared to be a strong barrier for hybridization in nature, in contradistinction to experiments which we reported earlier. We discuss the possibility of whole arm reciprocal translocations for mole voles. Our findings suggest that chromosomal translocations lead to diversification and speciation. |
topic |
chromosome painting karyotype mole vole speciation subterranean rodents |
url |
https://www.mdpi.com/1422-0067/20/18/4466 |
work_keys_str_mv |
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