ACE Insertion/Deletion Polymorphism and Diabetic Nephropathy: Clinical Implications of Genetic Information

Approximately 20–40% of diabetic patients develop nephropathy which is the leading cause of ESRD in developed countries. The ACE I/D polymorphism is thought to be a marker for functional polymorphism which regulates circulating and tissue ACE activity. While the initial study found a protective effe...

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Bibliographic Details
Main Author: Sung-Kyu Ha
Format: Article
Published: Hindawi Limited 2014-01-01
Series:Journal of Diabetes Research
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