Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9.

Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9.

Glioblastoma (GBM) is a highly infiltrative brain tumor in which cells with properties of stem cells, called glioblastoma stem cells (GSCs), have been identified. In general, the dominant view is that GSCs are responsible for the initiation, progression, invasion and recurrence of this tumor. In thi...

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Bibliographic Details
Main Authors: Justin V Joseph, Ingrid A M van Roosmalen, Ellen Busschers, Tushar Tomar, Siobhan Conroy, Ellie Eggens-Meijer, Natalia Peñaranda Fajardo, Milind M Pore, Veerakumar Balasubramanyian, Michiel Wagemakers, Sjef Copray, Wilfred F A den Dunnen, Frank A E Kruyt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4689519?pdf=render

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