Comparison of Maternal and Umbilical Cord Blood Selenium Levels in Low and Normal Birth Weight Neonates

• Main Authors: Lyly Nazemi, Mamak Shariat, Maryam Chamari, Reza Chahardoli, Leila Asgarzadeh, Fariba Seighali
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2015-10-01
• Series: Journal of Family and Reproductive Health
• Subjects: Selenium level; maternal blood; umbilical cord blood; LBW neonates; Normal birth weight neonates
• Online Access: https://jfrh.tums.ac.ir/index.php/jfrh/article/view/162
• ISSN: 1735-8949; 1735-9392

Objective:To compare the maternal and umbilical cord serum selenium concentrations in Low and normal birth weight neonates. Materials and methods:A case-control study was carried out in Vali-Asr and Akbarabadi Hospitals (Jan. to Dec. 2013). Two groups; case group; 91 mothers who delivered a low birth weight (LBW) neonate and control group; 86 subjects who delivered a normal birth weight neonate were selected. Immediately after birth, 5 ml of maternal blood and umbilical cord blood were collected, and sent to laboratory to assay Se concentrations. To compare both groups' blood Se concentration, data were analyzed in SPSS 16.0. Results:Eighty six (48.6%) mothers with normal birth weight neonates and 91 (51.4%) mothers with low birth weight infants entered the study. Mean maternal mothers' age and mean maternal blood Se were 28.55+5.90 years and 79.3756+26.46915. A significant association was seen between maternal blood and cord blood Se level in control and case group (P value<0.0001, r = 0.69) and (P value<0.001, r = 0.79). On the other hand no differences were seen between 2 groups' maternal blood Se level (P Value = 0.65). Umbilical Cord blood Se concentration was not also different between case and control group (P value = 0.46). Conclusion:We found that maternal and umbilical cord blood Se concentrations were not different in low and adequate birth weight infants, however; umbilical cord Se concentrations were positively correlated with maternal blood Se concentrations.