CD14 deficiency impacts glucose homeostasis in mice through altered adrenal tone.

The toll-like receptors comprise one of the most conserved components of the innate immune system, signaling the presence of molecules of microbial origin. It has been proposed that signaling through TLR4, which requires CD14 to recognize bacterial lipopolysaccharide (LPS), may generate low-grade in...

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Bibliographic Details
Main Authors: James L Young, Alfonso Mora, Anna Cerny, Michael P Czech, Bruce Woda, Evelyn A Kurt-Jones, Robert W Finberg, Silvia Corvera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3258240?pdf=render