Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress

Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress

The genetic component of Polycystic ovarian syndrome (PCOS) proved to play an important role in its etiology. Early androgenetic alopecia (EAGA) is widely accepted as its male equivalent of PCOS if it starts before age of 30. In this study, we aimed to investigate metabolic and oxidative stress para...

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Bibliographic Details
Main Authors: Didem Dereli Akdeniz, Ibrahim Omeroglu
Format: Article
Language:English
Published: Society of TURAZ AKADEMI 2021-06-01
Series:Medicine Science
Subjects:
early onset androgenetic alopecia
polycystic ovary syndrome
insulin resistance
oxidative stress
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=74747
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spelling doaj-220564062cfc4a4aa138a3e857c385f62021-08-24T22:56:29ZengSociety of TURAZ AKADEMI Medicine Science2147-06342021-06-011026091310.5455/medscience.2021.04.12774747Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stressDidem Dereli Akdeniz0Ibrahim Omeroglu1izmir economy university tepecik teaching and research hospitalThe genetic component of Polycystic ovarian syndrome (PCOS) proved to play an important role in its etiology. Early androgenetic alopecia (EAGA) is widely accepted as its male equivalent of PCOS if it starts before age of 30. In this study, we aimed to investigate metabolic and oxidative stress parameters of men with EAGA and compare them with healthy age-matched controls. Fasting glucose, fasting insulin, homocysteine, serum malondialdehyde (MDA), total antioxidant capacity (TAC), folic acid, and vitamin B12 were measured from the blood samples of thirty men with EAGA and 30 controls. Homeostasis model assessment (HOMA) results were used for the marker of insulin sensitivity. Alopecia classification was made by using the scale of Hamilton with Norwood modification. We demonstrated a significantly lower TAC activity (p [Med-Science 2021; 10(2.000): 609-13]http://www.ejmanager.com/fulltextpdf.php?mno=74747early onset androgenetic alopeciapolycystic ovary syndromeinsulin resistanceoxidative stress
collection DOAJ
language English
format Article
sources DOAJ
author Didem Dereli Akdeniz
Ibrahim Omeroglu
spellingShingle Didem Dereli Akdeniz
Ibrahim Omeroglu
Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress
Medicine Science
early onset androgenetic alopecia
polycystic ovary syndrome
insulin resistance
oxidative stress
author_facet Didem Dereli Akdeniz
Ibrahim Omeroglu
author_sort Didem Dereli Akdeniz
title Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress
title_short Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress
title_full Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress
title_fullStr Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress
title_full_unstemmed Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress
title_sort early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress
publisher Society of TURAZ AKADEMI
series Medicine Science
issn 2147-0634
publishDate 2021-06-01
description The genetic component of Polycystic ovarian syndrome (PCOS) proved to play an important role in its etiology. Early androgenetic alopecia (EAGA) is widely accepted as its male equivalent of PCOS if it starts before age of 30. In this study, we aimed to investigate metabolic and oxidative stress parameters of men with EAGA and compare them with healthy age-matched controls. Fasting glucose, fasting insulin, homocysteine, serum malondialdehyde (MDA), total antioxidant capacity (TAC), folic acid, and vitamin B12 were measured from the blood samples of thirty men with EAGA and 30 controls. Homeostasis model assessment (HOMA) results were used for the marker of insulin sensitivity. Alopecia classification was made by using the scale of Hamilton with Norwood modification. We demonstrated a significantly lower TAC activity (p [Med-Science 2021; 10(2.000): 609-13]
topic early onset androgenetic alopecia
polycystic ovary syndrome
insulin resistance
oxidative stress
url http://www.ejmanager.com/fulltextpdf.php?mno=74747
work_keys_str_mv AT didemdereliakdeniz earlyonsetandrogenicalopeciaasthemalephenotypicequivalentofpolycysticovariansyndromeisassociatedinhighoxidativestress
AT ibrahimomeroglu earlyonsetandrogenicalopeciaasthemalephenotypicequivalentofpolycysticovariansyndromeisassociatedinhighoxidativestress
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