Development of an engineered peptide antagonist against periostin to overcome doxorubicin resistance in breast cancer

Development of an engineered peptide antagonist against periostin to overcome doxorubicin resistance in breast cancer

Abstract Background Chemoresistance is one of the main problems in treatment of cancer. Periostin (PN) is a stromal protein which is mostly secreted from cancer associated fibroblasts in the tumor microenvironment and can promote cancer progression including cell survival, metastasis, and chemoresis...

Full description

Bibliographic Details
Main Authors: Khine Kyaw Oo, Thanpawee Kamolhan, Anish Soni, Suyanee Thongchot, Chalermchai Mitrpant, Pornchai O-charoenrat, Chanitra Thuwajit, Peti Thuwajit
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Cancer
Subjects:
Breast cancer
Periostin
Chemoresistance
Phage display 12-amino acids library
Doxorubicin
Online Access:https://doi.org/10.1186/s12885-020-07761-w

Internet

https://doi.org/10.1186/s12885-020-07761-w

Similar Items