K:D-Rib: cancer cell proliferation inibitor and DNAzyme folding promoter
We report the effects of K:D-Rib, a D-ribose and KHCO3 water solution on HTB-126 human cancer cell line proliferation and the preliminary ultraviolet-visible (UV-VIS) measures of DNAzyme as biosensor of extracellular K+ concentration. On the one hand, we demonstrate that the synergic action of KHCO3...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2014-01-01
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| Series: | Journal of Biological Research |
| Subjects: | |
| Online Access: | http://www.pagepressjournals.org/index.php/jbr/article/view/2135 |
| Summary: | We report the effects of K:D-Rib, a D-ribose and KHCO3 water solution on HTB-126 human cancer cell line proliferation and the preliminary ultraviolet-visible (UV-VIS) measures of DNAzyme as biosensor of extracellular K+ concentration. On the one hand, we demonstrate that the synergic action of KHCO3 and D-ribose from one side has a cytostatic effect on human breast cancer cell line increasing by 30% the doubling population time of treated cells with respect to the control; and on the other hand we demonstrate how it seems to permit the K+ uptake. |
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| ISSN: | 1826-8838 2284-0230 |