Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas

Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas

Sachin Jain,1 Ruolan Song,2 Jingwu Xie2 1Indiana University School of Medicine, 2Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indianapolis, IN, USA Abstract: The Hedgehog (Hh) pathway is critical for cell differentiation, tissue polarity, and stem cell maintenance during...

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Bibliographic Details
Main Authors: Jain S, Song R, Xie J
Format: Article
Language:English
Published: Dove Medical Press 2017-03-01
Series:OncoTargets and Therapy
Subjects:
Hedgehog
smoothened
inhibitor
cancer
basal cell carcinoma
Sonidegib
Online Access:https://www.dovepress.com/sonidegib-mechanism-of-action-pharmacology-and-clinical-utility-for-ad-peer-reviewed-article-OTT

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