Clinico-radiological Observations in Meconium Aspiration Syndrome
Introduction: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal. Methods: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of...
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doaj-228ed12218284dc3a0e11990de73025a2020-11-25T01:47:50ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2018-02-015620910.31729/jnma.3340Clinico-radiological Observations in Meconium Aspiration SyndromeSusana Lama0Shyam Kumar Mahato1Nagendra Chaudhary2Nikhil Agrawal3Santosh Pathak4Om Prakash Kurmi5Baldev Bhatia6Kailash Nath Agarwal7Department of Pediatrics, Universal College of Medical Sciences, Bhairahawa, NepalDepartment of Pediatrics, Universal College of Medical Sciences, Bhairahawa, NepalDepartment of Pediatrics, Universal College of Medical Sciences, Bhairahawa, Nepal, Centre for Population Health Research, Bhairahawa, NepalDepartment of Pediatrics, Universal College of Medical Sciences, Bhairahawa, NepalDepartment of Pediatrics, Chitwan Medical College, Bharatpur, NepalNuffield Department of Population Health, Clinical Trial Service Unit & Epidemiological Studies Unit, University of Oxford, Oxford, UK, Centre for Population Health Research, Bhairahawa, NepalDepartment of Pediatrics, Heritage Institute of Medical Sciences, Varanasi, IndiaDepartment of Pediatrics, Universal College of Medical Sciences, Bhairahawa, NepalIntroduction: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal. Methods: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of MAS in relation to gender, gestational age, mode of delivery, birth weight, Apgar score, thickness of meconium, age at admission and the immediate outcome were studied. Results: Out of 584 admitted newborns (male=389; female=186) during the study period, 78 (13.4%) had meconium aspiration syndrome with male: female ratio of 1.2:1. Majority of babies admitted to NICU had thick meconium [n=52 (66.7%)]. There was no statistical significant difference in various parameters such as Apgar score at 1 and 5 minutes, respiratory distress, birth asphyxia, duration of oxygen use, MAS severity and chest x-ray in those with thick MAS compared to thin. Among all newborns with MAS, 59% (n=46) had abnormal radiological findings with over two-folds in those with thick MAS (71.7%)] compared to thin (28%). Hyperinflation (47.8%), diffuse patchy infiltration (37%), consolidation (21.7%) collapse (8.7%), right lung fissure (6.5%) and pneumothorax (8.7%) were the abnormal radiological findings seen in MAS babies. The odds of having APGAR score at 1 minute at least 7 or more was twice unlikely in those having thick meconium compared to thin (P=0.02) Conclusions: Thick meconium is relatively common with more significant abnormal radiological findings and low Apgar score. https://www.jnma.com.np/jnma/index.php/jnma/article/view/3340 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Susana Lama Shyam Kumar Mahato Nagendra Chaudhary Nikhil Agrawal Santosh Pathak Om Prakash Kurmi Baldev Bhatia Kailash Nath Agarwal |
spellingShingle |
Susana Lama Shyam Kumar Mahato Nagendra Chaudhary Nikhil Agrawal Santosh Pathak Om Prakash Kurmi Baldev Bhatia Kailash Nath Agarwal Clinico-radiological Observations in Meconium Aspiration Syndrome Journal of Nepal Medical Association |
author_facet |
Susana Lama Shyam Kumar Mahato Nagendra Chaudhary Nikhil Agrawal Santosh Pathak Om Prakash Kurmi Baldev Bhatia Kailash Nath Agarwal |
author_sort |
Susana Lama |
title |
Clinico-radiological Observations in Meconium Aspiration Syndrome |
title_short |
Clinico-radiological Observations in Meconium Aspiration Syndrome |
title_full |
Clinico-radiological Observations in Meconium Aspiration Syndrome |
title_fullStr |
Clinico-radiological Observations in Meconium Aspiration Syndrome |
title_full_unstemmed |
Clinico-radiological Observations in Meconium Aspiration Syndrome |
title_sort |
clinico-radiological observations in meconium aspiration syndrome |
publisher |
Nepal Medical Association |
series |
Journal of Nepal Medical Association |
issn |
0028-2715 1815-672X |
publishDate |
2018-02-01 |
description |
Introduction: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal.
Methods: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of MAS in relation to gender, gestational age, mode of delivery, birth weight, Apgar score, thickness of meconium, age at admission and the immediate outcome were studied.
Results: Out of 584 admitted newborns (male=389; female=186) during the study period, 78 (13.4%) had meconium aspiration syndrome with male: female ratio of 1.2:1. Majority of babies admitted to NICU had thick meconium [n=52 (66.7%)]. There was no statistical significant difference in various parameters such as Apgar score at 1 and 5 minutes, respiratory distress, birth asphyxia, duration of oxygen use, MAS severity and chest x-ray in those with thick MAS compared to thin. Among all newborns with MAS, 59% (n=46) had abnormal radiological findings with over two-folds in those with thick MAS (71.7%)] compared to thin (28%). Hyperinflation (47.8%), diffuse patchy infiltration (37%), consolidation (21.7%) collapse (8.7%), right lung fissure (6.5%) and pneumothorax (8.7%) were the abnormal radiological findings seen in MAS babies. The odds of having APGAR score at 1 minute at least 7 or more was twice unlikely in those having thick meconium compared to thin (P=0.02)
Conclusions: Thick meconium is relatively common with more significant abnormal radiological findings and low Apgar score.
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url |
https://www.jnma.com.np/jnma/index.php/jnma/article/view/3340 |
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