Dynamic surveillance of tamoxifen‐resistance in ER‐positive breast cancer by CAIX‐targeted ultrasound imaging

Dynamic surveillance of tamoxifen‐resistance in ER‐positive breast cancer by CAIX‐targeted ultrasound imaging

Abstract Tamoxifen‐based hormone therapy is central for the treatment of estrogen receptor positive (ER+) breast cancer. However, the acquired tamoxifen resistance, typically co‐exists with hypoxia, remains a major challenge. We aimed to develop a non‐invasive, targeted ultrasound imaging approach t...

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Bibliographic Details
Main Authors: Ying Li, Xiaoyu Chen, ZhiWei Zhou, Qing Li, Kenneth D. Westover, Meng Wang, Junjun Liu, Sheng Zhang, Jin Zhang, Bo Xu, Xi Wei
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Cancer Medicine
Subjects:
breast cancer
hypoxia
PLGA‐PEG‐mAbCAIX nanobubbles
tamoxifen resistance
ultrasonographic imaging
Online Access:https://doi.org/10.1002/cam4.2878

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