Ecological multiplex interactions determine the role of species for parasite spread amplification
Despite their potential interplay, multiple routes of many disease transmissions are often investigated separately. As a unifying framework for understanding parasite spread through interdependent transmission paths, we present the ‘ecomultiplex’ model, where the multiple transmission paths among a...
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doaj-229f82a477134e1380259ebf2525e31a2021-05-05T15:49:10ZengeLife Sciences Publications LtdeLife2050-084X2018-04-01710.7554/eLife.32814Ecological multiplex interactions determine the role of species for parasite spread amplificationMassimo Stella0https://orcid.org/0000-0003-1810-9699Sanja Selakovic1Alberto Antonioni2https://orcid.org/0000-0002-5788-3348Cecilia S Andreazzi3https://orcid.org/0000-0002-9817-0635Institute for Complex Systems Simulation, University of Southampton, Southampton, United KingdomFaculty of Geosciences, Utrecht University, Utrecht, NetherlandsDepartment of Economics, University College London, London, United Kingdom; Grupo Interdisciplinar de Sistemas Complejos, Departamento de Matemáticas, Universidad Carlos III de Madrid, Madrid, Spain; Institute for Biocomputation and Physics of Complex Systems, University of Zaragoza, Zaragoza, SpainFiocruz Mata Atlântica, Fundação Oswaldo Cruz, Rio de Janeiro, BrazilDespite their potential interplay, multiple routes of many disease transmissions are often investigated separately. As a unifying framework for understanding parasite spread through interdependent transmission paths, we present the ‘ecomultiplex’ model, where the multiple transmission paths among a diverse community of interacting hosts are represented as a spatially explicit multiplex network. We adopt this framework for designing and testing potential control strategies for Trypanosoma cruzi spread in two empirical host communities. We show that the ecomultiplex model is an efficient and low data-demanding method to identify which species enhances parasite spread and should thus be a target for control strategies. We also find that the interplay between predator-prey and host-parasite interactions leads to a phenomenon of parasite amplification, in which top predators facilitate T. cruzi spread, offering a mechanistic interpretation of previous empirical findings. Our approach can provide novel insights in understanding and controlling parasite spreading in real-world complex systems.https://elifesciences.org/articles/32814ecological multiplex networksmulti-layer networksparasite spreadingmulti-host parasitesmultiple routes of transmissionimmunisation strategies |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Massimo Stella Sanja Selakovic Alberto Antonioni Cecilia S Andreazzi |
spellingShingle |
Massimo Stella Sanja Selakovic Alberto Antonioni Cecilia S Andreazzi Ecological multiplex interactions determine the role of species for parasite spread amplification eLife ecological multiplex networks multi-layer networks parasite spreading multi-host parasites multiple routes of transmission immunisation strategies |
author_facet |
Massimo Stella Sanja Selakovic Alberto Antonioni Cecilia S Andreazzi |
author_sort |
Massimo Stella |
title |
Ecological multiplex interactions determine the role of species for parasite spread amplification |
title_short |
Ecological multiplex interactions determine the role of species for parasite spread amplification |
title_full |
Ecological multiplex interactions determine the role of species for parasite spread amplification |
title_fullStr |
Ecological multiplex interactions determine the role of species for parasite spread amplification |
title_full_unstemmed |
Ecological multiplex interactions determine the role of species for parasite spread amplification |
title_sort |
ecological multiplex interactions determine the role of species for parasite spread amplification |
publisher |
eLife Sciences Publications Ltd |
series |
eLife |
issn |
2050-084X |
publishDate |
2018-04-01 |
description |
Despite their potential interplay, multiple routes of many disease transmissions are often investigated separately. As a unifying framework for understanding parasite spread through interdependent transmission paths, we present the ‘ecomultiplex’ model, where the multiple transmission paths among a diverse community of interacting hosts are represented as a spatially explicit multiplex network. We adopt this framework for designing and testing potential control strategies for Trypanosoma cruzi spread in two empirical host communities. We show that the ecomultiplex model is an efficient and low data-demanding method to identify which species enhances parasite spread and should thus be a target for control strategies. We also find that the interplay between predator-prey and host-parasite interactions leads to a phenomenon of parasite amplification, in which top predators facilitate T. cruzi spread, offering a mechanistic interpretation of previous empirical findings. Our approach can provide novel insights in understanding and controlling parasite spreading in real-world complex systems. |
topic |
ecological multiplex networks multi-layer networks parasite spreading multi-host parasites multiple routes of transmission immunisation strategies |
url |
https://elifesciences.org/articles/32814 |
work_keys_str_mv |
AT massimostella ecologicalmultiplexinteractionsdeterminetheroleofspeciesforparasitespreadamplification AT sanjaselakovic ecologicalmultiplexinteractionsdeterminetheroleofspeciesforparasitespreadamplification AT albertoantonioni ecologicalmultiplexinteractionsdeterminetheroleofspeciesforparasitespreadamplification AT ceciliasandreazzi ecologicalmultiplexinteractionsdeterminetheroleofspeciesforparasitespreadamplification |
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1721459750637404160 |