Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces
Abstract Microscale self‐propelled robots show great promise in the biomedical field and are the focus of many researchers. These tiny devices, which move and navigate by themselves, are typically based on inorganic microstructures that are not biodegradable and potentially toxic, often using toxic...
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doaj-22ad8129564743b384d6873be42291622021-10-08T09:03:05ZengWileyAdvanced Science2198-38442021-10-01819n/an/a10.1002/advs.202101301Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined SpacesCarmen C. Mayorga‐Martinez0Jaroslav Zelenka1Jan Grmela2Hana Michalkova3Tomáš Ruml4Jan Mareš5Martin Pumera6Center for Advanced Functional Nanorobots Department of Inorganic Chemistry University of Chemistry and Technology Prague Technicka 5, 166 28, Prague 6 Czech RepublicDepartment of Biochemistry and Microbiology University of Chemistry and Technology Prague Technicka 5, 166 28, Prague 6 Czech RepublicDepartment of Zoology Fisheries Hydrobiology and Apiculture Mendel University in Brno Zemedelska 1 Brno CZ‐61300 Czech RepublicDepartment of Chemistry and Biochemistry Mendel University in Brno Zemedelska 1 Brno CZ‐613 00 Czech RepublicDepartment of Biochemistry and Microbiology University of Chemistry and Technology Prague Technicka 5, 166 28, Prague 6 Czech RepublicDepartment of Zoology Fisheries Hydrobiology and Apiculture Mendel University in Brno Zemedelska 1 Brno CZ‐61300 Czech RepublicCenter for Advanced Functional Nanorobots Department of Inorganic Chemistry University of Chemistry and Technology Prague Technicka 5, 166 28, Prague 6 Czech RepublicAbstract Microscale self‐propelled robots show great promise in the biomedical field and are the focus of many researchers. These tiny devices, which move and navigate by themselves, are typically based on inorganic microstructures that are not biodegradable and potentially toxic, often using toxic fuels or elaborate external energy sources, which limits their real‐world applications. One potential solution to these issues is to go back to nature. Here, the authors use high‐speed Aqua Sperm micromotors obtained from North African catfish (Clarias gariepinus, B. 1822) to destroy bacterial biofilm. These Aqua Sperm micromotors use water‐induced dynein ATPase catalyzed adenosine triphosphate (ATP) degradation as biocompatible fuel to trigger their fast speed and snake‐like undulatory locomotion that facilitate biofilm destruction in less than one minute. This efficient biofilm destruction is due to the ultra‐fast velocity as well as the head size of Aqua Sperm micromotors being similar to bacteria, which facilitates their entry to and navigation within the biofilm matrix. In addition, the authors demonstrate the real‐world application of Aqua Sperm micromotors by destroying biofilms that had colonized medical and laboratory tubing. The implemented system extends the biomedical application of Aqua Sperm micromotors to include hybrid robots for fertilization or cargo tasks.https://doi.org/10.1002/advs.202101301active bacterial biofilmsAqua Sperm micromotorsbiobotsnanorobotsspermatozoaspermbots |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Carmen C. Mayorga‐Martinez Jaroslav Zelenka Jan Grmela Hana Michalkova Tomáš Ruml Jan Mareš Martin Pumera |
spellingShingle |
Carmen C. Mayorga‐Martinez Jaroslav Zelenka Jan Grmela Hana Michalkova Tomáš Ruml Jan Mareš Martin Pumera Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces Advanced Science active bacterial biofilms Aqua Sperm micromotors biobots nanorobots spermatozoa spermbots |
author_facet |
Carmen C. Mayorga‐Martinez Jaroslav Zelenka Jan Grmela Hana Michalkova Tomáš Ruml Jan Mareš Martin Pumera |
author_sort |
Carmen C. Mayorga‐Martinez |
title |
Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces |
title_short |
Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces |
title_full |
Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces |
title_fullStr |
Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces |
title_full_unstemmed |
Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces |
title_sort |
swarming aqua sperm micromotors for active bacterial biofilms removal in confined spaces |
publisher |
Wiley |
series |
Advanced Science |
issn |
2198-3844 |
publishDate |
2021-10-01 |
description |
Abstract Microscale self‐propelled robots show great promise in the biomedical field and are the focus of many researchers. These tiny devices, which move and navigate by themselves, are typically based on inorganic microstructures that are not biodegradable and potentially toxic, often using toxic fuels or elaborate external energy sources, which limits their real‐world applications. One potential solution to these issues is to go back to nature. Here, the authors use high‐speed Aqua Sperm micromotors obtained from North African catfish (Clarias gariepinus, B. 1822) to destroy bacterial biofilm. These Aqua Sperm micromotors use water‐induced dynein ATPase catalyzed adenosine triphosphate (ATP) degradation as biocompatible fuel to trigger their fast speed and snake‐like undulatory locomotion that facilitate biofilm destruction in less than one minute. This efficient biofilm destruction is due to the ultra‐fast velocity as well as the head size of Aqua Sperm micromotors being similar to bacteria, which facilitates their entry to and navigation within the biofilm matrix. In addition, the authors demonstrate the real‐world application of Aqua Sperm micromotors by destroying biofilms that had colonized medical and laboratory tubing. The implemented system extends the biomedical application of Aqua Sperm micromotors to include hybrid robots for fertilization or cargo tasks. |
topic |
active bacterial biofilms Aqua Sperm micromotors biobots nanorobots spermatozoa spermbots |
url |
https://doi.org/10.1002/advs.202101301 |
work_keys_str_mv |
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