Sesquiterpene lactones derived from Saussurea lappa induce apoptosis and inhibit invasion and migration in neuroblastoma cells

Sesquiterpene lactones derived from Saussurea lappa induce apoptosis and inhibit invasion and migration in neuroblastoma cells

Neuroblastoma is among the most fatal of solid tumors in the pediatric age group, even when treated aggressively. Therefore, a new effective therapeutic drug(s) for neuroblastoma is urgently needed. To clarify the anticancer effects of the sesquiterpene lactones dehydrocostus lactone and costunolide...

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Bibliographic Details
Main Authors: Keiichi Tabata, Yuki Nishimura, Taiji Takeda, Masahiro Kurita, Taketo Uchiyama, Takashi Suzuki
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Journal of Pharmacological Sciences
Subjects:
Sesquiterpenes
Neuroblastoma
Apoptosis
Invasion
Migration
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315000055

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