Clinical, Immunological, and Molecular Profile of Chronic Granulomatous Disease: A Multi-Centric Study of 236 Patients From India

Clinical, Immunological, and Molecular Profile of Chronic Granulomatous Disease: A Multi-Centric Study of 236 Patients From India

BackgroundChronic granulomatous disease (CGD) is an inherited defect in phagocytic respiratory burst that results in severe and life-threatening infections in affected children. Single center studies from India have shown that proportion of autosomal recessive (AR) CGD is more than that reported fro...

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Main Authors: Amit Rawat, Pandiarajan Vignesh, Murugan Sudhakar, Madhubala Sharma, Deepti Suri, Ankur Jindal, Anju Gupta, Jitendra Kumar Shandilya, Sathish Kumar Loganathan, Gurjit Kaur, Sanchi Chawla, Pratap Kumar Patra, Alka Khadwal, Biman Saikia, Ranjana Walker Minz, Vaishali Aggarwal, Prasad Taur, Ambreen Pandrowala, Vijaya Gowri, Mukesh Desai, Manasi Kulkarni, Gauri Hule, Umair Bargir, Priyanka Kambli, Manisha Madkaikar, Sagar Bhattad, Chetan Ginigeri, Harish Kumar, Ananthvikas Jayaram, Deenadayalan Munirathnam, Meena Sivasankaran, Revathi Raj, Ramya Uppuluri, Fouzia Na, Biju George, Harsha Prasada Lashkari, Manas Kalra, Anupam Sachdeva, Shishir Seth, Tapas Sabui, Aman Gupta, Karin van Leeuwen, Martin de Boer, Koon Wing Chan, Kohsuke Imai, Osamu Ohara, Shigeaki Nonoyama, Yu Lung Lau, Surjit Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
Chronic Granulomatous Disease
India
Mycobacterium tuberculosis
Bacillus Calmette Guerin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.625320/full

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