Altered islet morphology but normal islet secretory function in vitro in a mouse model with microvascular alterations in the pancreas.
BACKGROUND:Our previous studies have shown that signal transducer and activator of transcription 3 (STAT3) signaling is important for the development of pancreatic microvasculature via its regulation of vascular endothelial growth factor-A (VEGF-A). Pancreas-specific STAT3-KO mice exhibit glucose in...
Main Authors: | Elena Kostromina, Xiaorui Wang, Weiping Han |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3726616?pdf=render |
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