Asthma-Associated Long TSLP Inhibits the Production of IgA

Asthma-Associated Long TSLP Inhibits the Production of IgA

Thymic stromal lymphopoietin (TSLP) contributes to asthmatic disease. The concentrations of protective IgA may be reduced in the respiratory tract of asthma patients. We investigated how homeostatic short TSLP (shTSLP) and asthma-associated long TSLP (loTSLP) regulate IgA production. B cells from he...

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Bibliographic Details
Main Authors: Dorianne van Heerden, Robert S. van Binnendijk, Samantha A. M. Tromp, Huub F. J. Savelkoul, R. J. Joost van Neerven, Gerco den Hartog
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
short and long TSLP
asthma
IgA
memory B cells
IL-4
IL-13
Online Access:https://www.mdpi.com/1422-0067/22/7/3592

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