C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin

C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin

A new direction for the treatment of skeletal myopathies, which are mainly caused by abnormal mitochondrial metabolism, is the application of drugs and active substances to relieve oxidative stress in mitochondria. Phloretin, a dihydrochalcone active substance widely present in succulent fruits, has...

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Bibliographic Details
Main Authors: Jie Li, Qing Yang, Lin Han, Chuanying Pan, Chuzhao Lei, Hong Chen, Xianyong Lan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
phloretin
skeletal myopathies diseases
C2C12 myoblasts
AMPK
antioxidative
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.541260/full

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