Identification and Validation of an Antivirulence Agent Targeting HlyU-Regulated Virulence in Vibrio vulnificus

Identification and Validation of an Antivirulence Agent Targeting HlyU-Regulated Virulence in Vibrio vulnificus

Antimicrobial resistance (AMR) in pathogens is the result of indiscriminate use of antibiotics and consequent metabolic/genetic modulation to evolve survival strategies and clonal-selection in AMR strains. As an alternative to antibiotic treatment, antivirulence strategies are being developed, not o...

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Bibliographic Details
Main Authors: Saba Imdad, Akhilesh Kumar Chaurasia, Kyeong Kyu Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Vibrio vulnificus
rtxA1
hemolysin
hlyU
drug identification and repositioning
fursultiamine hydrochloride
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00152/full

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