Curcumin Induced Human Gastric Cancer BGC-823 Cells Apoptosis by ROS-Mediated ASK1-MKK4-JNK Stress Signaling Pathway

Curcumin Induced Human Gastric Cancer BGC-823 Cells Apoptosis by ROS-Mediated ASK1-MKK4-JNK Stress Signaling Pathway

The signaling mediated by stress-activated MAP kinases (MAPK), c-Jun N-terminal kinase (JNK) has well-established importance in cancer. In the present report, we investigated the effects of curcumin on the signaling pathway in human gastric cancer BGC-823 cells. Curcumin induced reactive oxygen spe...

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Bibliographic Details
Main Authors:	Tao Liang, Xiaojian Zhang, Wenhua Xue, Songfeng Zhao, Xiang Zhang, Jianying Pei
Format:	Article
Language:	English
Published:	MDPI AG 2014-09-01
Series:	International Journal of Molecular Sciences
Subjects:	curcumin gastric cancer ROS ASK1-MKK4-JNK apoptosis
Online Access:	http://www.mdpi.com/1422-0067/15/9/15754

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