IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway.

IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway.

Interleukin-7 (IL-7) concentrations are increased in the blood of CD4+ T cell depleted individuals, including HIV-1 infected patients. High IL-7 levels might stimulate T cell activation and, as we have shown earlier, IL-7 can prime resting T cell to CD95 induced apoptosis as well. HIV-1 infection le...

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Bibliographic Details
Main Authors: Stefano Sammicheli, Vu Phuong Linh Dang, Nicolas Ruffin, Hong Thang Pham, Rebecka Lantto, Nancy Vivar, Francesca Chiodi, Bence Rethi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3237470?pdf=render

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