Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans

Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans

Abstract Background Sulfate modification of N-glycans is important for several biological functions such as clearance of pituitary hormones or immunoregulation. Yet, the prevalence of this N-glycan modification and its functions remain largely unexplored. Characterization of N-glycans bearing sulfat...

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Bibliographic Details
Main Authors: Léa Chuzel, Samantha L. Fossa, Madison L. Boisvert, Samanta Cajic, René Hennig, Mehul B. Ganatra, Udo Reichl, Erdmann Rapp, Christopher H. Taron
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Microbial Cell Factories
Subjects:
Sulfatase
Functional metagenomics
Glycoanalytics
Glycan analysis
Human microbiome
Glycan sulfation
Online Access:https://doi.org/10.1186/s12934-021-01652-w

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