Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish.
Development and function of tissues and organs are powered by the activity of mitochondria. In humans, inherited genetic mutations that lead to progressive mitochondrial pathology often manifest during infancy and can lead to death, reflecting the indispensable nature of mitochondrial biogenesis and...
Main Authors: | Anna M Sokol, Barbara Uszczynska-Ratajczak, Michelle M Collins, Michal Bazala, Ulrike Topf, Pia R Lundegaard, Sreedevi Sugunan, Stefan Guenther, Carsten Kuenne, Johannes Graumann, Sherine S L Chan, Didier Y R Stainier, Agnieszka Chacinska |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-11-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC6245507?pdf=render |
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