Usage of Multimodal Evoked Potentials in Diagnosis of Changes in Central Nervous System in Multiple Sclerosis
OBJECTIVE: Evoked potentials are used in the functional assessment of sensory and motor pathways. Conflicting results have been reported in different studies about the value of evoked potentials in demyelinating diseases. Over 80% of patients with multiple sclerosis present with a relapsing–remittin...
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Galenos Yayinevi
2011-03-01
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doaj-2350a8832ca049469095691c92bc81662021-09-02T18:35:31ZengGalenos YayineviTürk Nöroloji Dergisi1301-062X1309-25452011-03-011713844Usage of Multimodal Evoked Potentials in Diagnosis of Changes in Central Nervous System in Multiple SclerosisBahar Özbek0Kemal Balcı1Yahya Çelik2University Of Trakya, School Of Medicine, Department Of Neurology, EdirneUniversity Of Trakya, School Of Medicine, Department Of Neurology, EdirneUniversity Of Trakya, School Of Medicine, Department Of Neurology, EdirneOBJECTIVE: Evoked potentials are used in the functional assessment of sensory and motor pathways. Conflicting results have been reported in different studies about the value of evoked potentials in demyelinating diseases. Over 80% of patients with multiple sclerosis present with a relapsing–remitting form of the disease. In this study we aimed to examine the value of each evoked potential to demonstrate the demyelinating lesions in a homogenous group of patients with relapsing remitting multiple sclerosis. We also aimed to examine the correlation between clinical status and evoked potential abnormalities. METHODS: Twenty patients with relapsing remitting multiple sclerosis and ten healthy volunteers were included in the study to evaluate the value of evoked potentials in a homogenous group. Visual, somatosensory and motor evoked potentials were measured and EDSS scores of the patients were calculated. RESULTS: Of 20 patients, 15 patients(75%) had VEP abnormality, 14 patients (70%) had MEP abnormality and 12 patients (60%) had tibial SEP abnormality. All patients had at least one abnormal evoked potential measurement. The abnormality of evoked potentials also had a correlation with high EDSS scores. CONCLUSION: We concluded that evoked potentials, especially used in combination, are good markers to show the nervous damage in patients with multiple sclerosishttp://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-23008Relapsing Remitting Multiple Sclerosisvisual evoked potentialmotor evoked potentialsomatosensory evoked potential |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bahar Özbek Kemal Balcı Yahya Çelik |
spellingShingle |
Bahar Özbek Kemal Balcı Yahya Çelik Usage of Multimodal Evoked Potentials in Diagnosis of Changes in Central Nervous System in Multiple Sclerosis Türk Nöroloji Dergisi Relapsing Remitting Multiple Sclerosis visual evoked potential motor evoked potential somatosensory evoked potential |
author_facet |
Bahar Özbek Kemal Balcı Yahya Çelik |
author_sort |
Bahar Özbek |
title |
Usage of Multimodal Evoked Potentials in Diagnosis of Changes in Central Nervous System in Multiple Sclerosis |
title_short |
Usage of Multimodal Evoked Potentials in Diagnosis of Changes in Central Nervous System in Multiple Sclerosis |
title_full |
Usage of Multimodal Evoked Potentials in Diagnosis of Changes in Central Nervous System in Multiple Sclerosis |
title_fullStr |
Usage of Multimodal Evoked Potentials in Diagnosis of Changes in Central Nervous System in Multiple Sclerosis |
title_full_unstemmed |
Usage of Multimodal Evoked Potentials in Diagnosis of Changes in Central Nervous System in Multiple Sclerosis |
title_sort |
usage of multimodal evoked potentials in diagnosis of changes in central nervous system in multiple sclerosis |
publisher |
Galenos Yayinevi |
series |
Türk Nöroloji Dergisi |
issn |
1301-062X 1309-2545 |
publishDate |
2011-03-01 |
description |
OBJECTIVE: Evoked potentials are used in the functional assessment of sensory and motor pathways. Conflicting results have been reported in different studies about the value of evoked potentials in demyelinating diseases. Over 80% of patients with multiple sclerosis present with a relapsing–remitting form of the disease. In this study we aimed to examine the value of each evoked potential to demonstrate the demyelinating lesions in a homogenous group of patients with relapsing remitting multiple sclerosis. We also aimed to examine the correlation between clinical status and evoked potential abnormalities.
METHODS: Twenty patients with relapsing remitting multiple sclerosis and ten healthy volunteers were included in the study to evaluate the value of evoked potentials in a homogenous group. Visual, somatosensory and motor evoked potentials were measured and EDSS scores of the patients were calculated.
RESULTS: Of 20 patients, 15 patients(75%) had VEP abnormality, 14 patients (70%) had MEP abnormality and 12 patients (60%) had tibial SEP abnormality. All patients had at least one abnormal evoked potential measurement. The abnormality of evoked potentials also had a correlation with high EDSS scores.
CONCLUSION: We concluded that evoked potentials, especially used in combination, are good markers to show the nervous damage in patients with multiple sclerosis |
topic |
Relapsing Remitting Multiple Sclerosis visual evoked potential motor evoked potential somatosensory evoked potential |
url |
http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-23008 |
work_keys_str_mv |
AT baharozbek usageofmultimodalevokedpotentialsindiagnosisofchangesincentralnervoussysteminmultiplesclerosis AT kemalbalcı usageofmultimodalevokedpotentialsindiagnosisofchangesincentralnervoussysteminmultiplesclerosis AT yahyacelik usageofmultimodalevokedpotentialsindiagnosisofchangesincentralnervoussysteminmultiplesclerosis |
_version_ |
1721171470525136896 |