Activation of P2X7 promotes cerebral edema and neurological injury after traumatic brain injury in mice.
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Cerebral edema, the abnormal accumulation of fluid within the brain parenchyma, contributes to elevated intracranial pressure (ICP) and is a common life-threatening neurological complication following TBI. Unfortunate...
Main Authors: | Donald E Kimbler, Jessica Shields, Nathan Yanasak, John R Vender, Krishnan M Dhandapani |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22815977/pdf/?tool=EBI |
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