Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons
Summary: Control of CNS pathogens by CD8 T cells is key to avoid fatal neuroinflammation. Yet, the modalities of MHC I presentation in the brain are poorly understood. Here, we analyze the antigen presentation mechanisms underlying CD8 T cell-mediated control of the Toxoplasma gondii parasite in the...
Main Authors: | Anna Salvioni, Marcy Belloy, Aurore Lebourg, Emilie Bassot, Vincent Cantaloube-Ferrieu, Virginie Vasseur, Sophie Blanié, Roland S. Liblau, Elsa Suberbielle, Ellen A. Robey, Nicolas Blanchard |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-06-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124719306801 |
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