Use of Supplemented or Human Material to Simulate PD Behavior of Antibiotics at the Target Site In Vitro

In antimicrobial drug development, in vitro antibiotic susceptibility testing is conducted in standard growth media, such as Mueller–Hinton broth (MHB). These growth media provide optimal bacterial growth, but do not consider certain host factors that would be necessary to mimic the in vivo bacteria...

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Bibliographic Details
Main Authors: Alina Nussbaumer-Pröll, Markus Zeitlinger
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pharmaceutics
Subjects:
PD
MIC
TKC
Online Access:https://www.mdpi.com/1999-4923/12/8/773