| Summary: | Optogenetics has revolutionised research in cell biology over the past 15 years, yet devices that can effectively stimulate cells using light are often costly and specifically designed for a single experimental set-up with little flexibility. Our novel ‘OptoGenie’ stimulation device can be conveniently transferred between cell culture incubators for long-term stimulation, electrophysiology rigs for patch-clamp recordings, and optical microscopes for fluorescence imaging of cells. The modular design of the device offers portability between these experimental set-ups, is low cost compared with commercial devices, and provides easy adjustment of the stimulation intensity and frequency. OptoGenie provides an open-source model made from proprietary parts such that researchers without experience with electronics and coding can easily purchase, assemble and customise for their experimental needs.
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