Sleep and cognitive dysfunctions. Therapeutic approach

• Main Authors: M.G. Poluektov, I.S. Preobrazhenskaya
• Format: Article
• Language: Russian
• Published: IMA-PRESS LLC 2014-05-01
• Series: Nevrologiâ, Nejropsihiatriâ, Psihosomatika
• Subjects: cognitive impairment; mild cognitive impairment; dementia; alzheimer's disease; vascular dementia; vascular cognitive impair- ment; sleep disorders; egb 761; melatonin-based drugs.
• Online Access: https://nnp.ima-press.net/nnp/article/view/379

This review focuses on the possible mechanisms of sleep disorders in patients with cognitive impairment (CI) of different severity. The interrelation between CI, emotional disorders and insomnia, as well as the dependence of CI severity on the degree of sleep disorders, are discussed. The issues related to treatment of sleep disorders in patients with CI, the advantages and disadvantages of modern somnogenic medications are studied. Recommendations on management of patients with a combination of sleep disorders and CI are provided. Data on the use of Egb 761 to treat CI no dementia and melatonin-based drugs to treat sleep disorders in patients with CI are presented.