| Summary: | Osteoporosis is a systemic metabolic disease which is characterized by low bone mass and microarchitectural damage of bone tissue resulting in increased bone fragility. History, physical examination, laboratory investigations and different imaging technics are used in diagnosis of osteoporosis. Quantitative ultrasound (QUS) is an alternative method for diagnosis of osteoporosis and evaluation of fracture risk. In this study we aimed to evaluate the association between quantitative ultrasound values and pain and demographic features in pre- and postmenopausal women.
One hundred voluntary women aged over 40 years who were admitted to hospital in one day were included. Eight of these were excluded for different reasons. Demographic features and pain parameters were inquired. Quantitative ultrasound evaluation was performed with Hologic Sahara Clinical Bone Sonometer equipment. Speed of sound (SOS) and broadband ultrasound attenuation (BUA) values and stiffness parameters were used for evaluation.
Twenty four (26.1%) of the objects were premenopausal and 68 (73.9%) were postmenopausal. 24 (100%) of premenopausal objects and 57 (% 83.8) of postmenopausal objects had pain (p=0.061). In evaluation with QUS, mean BUA values were 67.9 ± 13.5 in premenopausal and 60.0 ± 15.8 in postmenopausal women (p=0.026). Mean stiffness values were found 91.2 ± 13.6 in premenopausal and 80.1 ± 17.6 in postmenopausal women (p=0.013). In all of the subjects, QUS parameters were found negatively corraleted with age, while no relationship was found with occupation, education level, body mass index (BMI) and pain.
Consequently, we found negative correlation between age and QUS parameters, but for other demographic features there was no correlation. This study will be more sensitive and specific if performed on more patients and supported by other measurement methods.
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