Unfolding Role of a Danger Molecule Adenosine Signaling in Modulation of Microbial Infection and Host Cell Response

Unfolding Role of a Danger Molecule Adenosine Signaling in Modulation of Microbial Infection and Host Cell Response

Ectonucleotidases CD39 and CD73, specific nucleotide metabolizing enzymes located on the surface of the host, can convert a pro-inflammatory environment driven by a danger molecule extracellular-ATP to an adenosine-mediated anti-inflammatory milieu. Accordingly, CD39/CD73 signaling has been strongly...

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Bibliographic Details
Main Authors:	Jaden S. Lee, Özlem Yilmaz
Format:	Article
Language:	English
Published:	MDPI AG 2018-01-01
Series:	International Journal of Molecular Sciences
Subjects:	purinergic signaling danger signal adenosine adenosine receptor CD39/CD73 opportunistic infections persistent pathogens chronic inflammatory diseases
Online Access:	http://www.mdpi.com/1422-0067/19/1/199

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