Iron deposits in the knee joints of a thalassemic patient
The overall prognosis for patients with ß-thalassemia has improved considerably during the past decades mainly due to regular blood transfusions, improvements in chelation therapy, and enhanced surveillance with imaging studies examining iron overload and other clinical complications. However, the p...
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doaj-23dbe4c184b94be193b18c7c9c1efd3c2020-11-25T03:07:31ZengSAGE PublishingActa Radiologica Open2058-46012058-46012013-02-01211510.1177/204798161347740110.1177_2047981613477401Iron deposits in the knee joints of a thalassemic patientCharalambos P EconomidesElpidoforos S SoteriadesMichalis HadjigavrielIoannis SeimenisApostolos KarantanasThe overall prognosis for patients with ß-thalassemia has improved considerably during the past decades mainly due to regular blood transfusions, improvements in chelation therapy, and enhanced surveillance with imaging studies examining iron overload and other clinical complications. However, the prolonged survival of these patients leads to the development of other health problems including degenerative diseases such as arthropathies, which require further attention since they have a significant impact on the quality of life. In the current case report, we present a 45-year-old white man with ß-thalassemia complaining of non-traumatic pain and restriction in the range of motion of both knees. Magnetic resonance imaging (MRI) revealed a tear in the medial meniscus of the left knee as well as iron deposits in both knees. Histological findings confirmed the presence of hemosiderin in both joints. To our knowledge, this is the first reported case of macroscopically documented iron deposits in the knee joints of a patient with ß-thalassemia using MRI.http://arr.sagepub.com/content/2/1/1.full.pdf |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Charalambos P Economides Elpidoforos S Soteriades Michalis Hadjigavriel Ioannis Seimenis Apostolos Karantanas |
spellingShingle |
Charalambos P Economides Elpidoforos S Soteriades Michalis Hadjigavriel Ioannis Seimenis Apostolos Karantanas Iron deposits in the knee joints of a thalassemic patient Acta Radiologica Open |
author_facet |
Charalambos P Economides Elpidoforos S Soteriades Michalis Hadjigavriel Ioannis Seimenis Apostolos Karantanas |
author_sort |
Charalambos P Economides |
title |
Iron deposits in the knee joints of a thalassemic patient |
title_short |
Iron deposits in the knee joints of a thalassemic patient |
title_full |
Iron deposits in the knee joints of a thalassemic patient |
title_fullStr |
Iron deposits in the knee joints of a thalassemic patient |
title_full_unstemmed |
Iron deposits in the knee joints of a thalassemic patient |
title_sort |
iron deposits in the knee joints of a thalassemic patient |
publisher |
SAGE Publishing |
series |
Acta Radiologica Open |
issn |
2058-4601 2058-4601 |
publishDate |
2013-02-01 |
description |
The overall prognosis for patients with ß-thalassemia has improved considerably during the past decades mainly due to regular blood transfusions, improvements in chelation therapy, and enhanced surveillance with imaging studies examining iron overload and other clinical complications. However, the prolonged survival of these patients leads to the development of other health problems including degenerative diseases such as arthropathies, which require further attention since they have a significant impact on the quality of life. In the current case report, we present a 45-year-old white man with ß-thalassemia complaining of non-traumatic pain and restriction in the range of motion of both knees. Magnetic resonance imaging (MRI) revealed a tear in the medial meniscus of the left knee as well as iron deposits in both knees. Histological findings confirmed the presence of hemosiderin in both joints. To our knowledge, this is the first reported case of macroscopically documented iron deposits in the knee joints of a patient with ß-thalassemia using MRI. |
url |
http://arr.sagepub.com/content/2/1/1.full.pdf |
work_keys_str_mv |
AT charalambospeconomides irondepositsinthekneejointsofathalassemicpatient AT elpidoforosssoteriades irondepositsinthekneejointsofathalassemicpatient AT michalishadjigavriel irondepositsinthekneejointsofathalassemicpatient AT ioannisseimenis irondepositsinthekneejointsofathalassemicpatient AT apostoloskarantanas irondepositsinthekneejointsofathalassemicpatient |
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