Gene design, optimization of protein expression and preliminary evaluation of a new chimeric protein for the serological diagnosis of both human and canine visceral leishmaniasis.

<h4>Background</h4>Visceral leishmaniasis (VL) is a major neglected disease, potentially fatal, whose control is still impaired by inefficient and/or expensive treatment and diagnostic methods. The most promising approach for VL diagnosis uses serological assays with recombinant proteins...

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Bibliographic Details
Main Authors: Wagner J T Santos, Diego H C Tavares, Artur L Castro Neto, Marília B Nascimento, Rafael Dhalia, Alessandra L Albuquerque, Carlos H N Costa, Franklin B Magalhães, Antônio M Rezende, Osvaldo P de Melo Neto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008488