A polymorphic 3'UTR element in ATP1B1 regulates alternative polyadenylation and is associated with blood pressure.
Although variants in many genes have previously been shown to be associated with blood pressure (BP) levels, the molecular mechanism underlying these associations are mostly unknown. We identified a multi-allelic T-rich sequence (TRS) in the 3'UTR of ATP1B1 that varies in length and sequence co...
Main Authors: | Megana K Prasad, Kavita Bhalla, Zhen Hua Pan, Jeffrey R O'Connell, Alan B Weder, Aravinda Chakravarti, Bin Tian, Yen-Pei C Chang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3788127?pdf=render |
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