Cytotoxic helix-rich oligomer formation by melittin and pancreatic polypeptide.
Conversion of amyloid fibrils by many peptides/proteins involves cytotoxic helix-rich oligomers. However, their toxicity and biophysical studies remain largely unknown due to their highly dynamic nature. To address this, we chose two helical peptides (melittin, Mel and pancreatic polypeptide, PP) an...
Main Authors: | Pradeep K Singh, Dhiman Ghosh, Debanjan Tewari, Ganesh M Mohite, Edmund Carvalho, Narendra Nath Jha, Reeba S Jacob, Shruti Sahay, Rinti Banerjee, Amal K Bera, Samir K Maji |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4372375?pdf=render |
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