Growth differentiation factor 11 attenuates cardiac ischemia reperfusion injury via enhancing mitochondrial biogenesis and telomerase activity
Abstract It has been reported that growth differentiation factor 11 (GDF11) protects against myocardial ischemia/reperfusion (IR) injury, but the underlying mechanisms have not been fully clarified. Considering that GDF11 plays a role in the aging/rejuvenation process and that aging is associated wi...
Main Authors: | Lin Chen, Guangjin Luo, Yameng Liu, Hairuo Lin, Cankun Zheng, Dongxiao Xie, Yingqi Zhu, Lu Chen, Xiaoxia Huang, Donghong Hu, Jiahe Xie, Zhenhuan Chen, Wangjun Liao, Jianping Bin, Qiancheng Wang, Yulin Liao |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03954-8 |
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