Interferon-β 1a and SARS Coronavirus Replication

Interferon-β 1a and SARS Coronavirus Replication

A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort...

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Bibliographic Details
Main Authors: Lisa E. Hensley, Elizabeth A. Fritz, Peter B. Jahrling, Christopher Karp, John W. Huggins, Thomas W. Geisbert
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2004-02-01
Series:Emerging Infectious Diseases
Subjects:
SARS
interferon
coronavirus
treatment
therapy
Online Access:https://wwwnc.cdc.gov/eid/article/10/2/03-0482_article
Description
Summary:A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort is under way to identify and test promising antiviral drugs. Here, we report that recombinant human interferon (IFN)-β 1a potently inhibits SARS coronavirus replication in vitro.
ISSN:1080-6040
1080-6059

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