MMP8 increases tongue carcinoma cell–cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5
Abstract Matrix metalloproteinases (MMPs) modify bioactive factors via selective processing or degradation resulting in tumour-promoting or tumour-suppressive effects, such as those by MMP8 in various cancers. We mapped the substrates of MMP8 to elucidate its previously shown tumour-protective role...
Main Authors: | K. Juurikka, A. Dufour, K. Pehkonen, B. Mainoli, P. Campioni Rodrigues, N. Solis, T. Klein, P. Nyberg, C. M. Overall, T. Salo, P. Åström |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-05-01
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Series: | Oncogenesis |
Online Access: | https://doi.org/10.1038/s41389-021-00334-x |
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