Management of locally advanced primary mediastinal synovial sarcoma

• Main Authors: Ambarish S Chatterjee, Rajiv Kumar, Nilendu Purandare, Sabita Jiwnani, George Karimundackal, C S Pramesh
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2017-01-01
• Series: Lung India
• Subjects: Locally advanced; neoadjuvant chemotherapy; primary mediastinal synovial sarcoma; R0-resection
• Online Access: http://www.lungindia.com/article.asp?issn=0970-2113;year=2017;volume=34;issue=2;spage=185;epage=188;aulast=Chatterjee

Primary mediastinal synovial sarcoma (PMSS) is a relatively rare disease, and patients are treated predominantly with surgery for resectable disease. Management of locally advanced borderline resectable and unresectable PMSS is not only challenging but also lacks standard guidelines. We present three patients with PMSS, who were unresectable or borderline resectable at presentation and were treated with neoadjuvant chemotherapy followed by surgery and postoperative radiotherapy.