Fluorescence-based Techniques to Study the Structure and Dynamics of Mass-selected Biomolecular Ions
Laser-induced fluorescence studies on mass-selected biomolecules are a promising route to understand their properties in the gas phase and probe their intrinsic properties in a solvent-free environment. Fluorescence has been used to investigate the conformation and dynamics of gaseous biomolecular i...
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doaj-24686fa610b64b39bdc637d2bd6a539d2021-05-06T08:01:25ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242021-04-0175425225610.2533/chimia.2021.252Fluorescence-based Techniques to Study the Structure and Dynamics of Mass-selected Biomolecular IonsPrince Tiwari0ETH Zürich, Department of Chemistry and Applied Biosciences, Vladimir-Prelog-Weg 3, CH-8093 Zürich, SwitzerlandLaser-induced fluorescence studies on mass-selected biomolecules are a promising route to understand their properties in the gas phase and probe their intrinsic properties in a solvent-free environment. Fluorescence has been used to investigate the conformation and dynamics of gaseous biomolecular ions. With Förster Resonance Energy Transfer (FRET), it is now possible to obtain sensitive intramolecular distance information from large biomolecules, like proteins, with high chemical specificity. With growing interest and applications, gas-phase fluorescence measurements can shed greater light on the characteristics of proteins in the gas phase. Compared to the solution phase measurements, gas-phase fluorescence can also help understand the influence of solvent interactions on the protein structure and function.https://www.ingentaconnect.com/contentone/scs/chimia/2021/00000075/00000004/art00002biomolecular structuredynamicsfluoresenceion spectroscopymass spectrometry |
collection |
DOAJ |
language |
deu |
format |
Article |
sources |
DOAJ |
author |
Prince Tiwari |
spellingShingle |
Prince Tiwari Fluorescence-based Techniques to Study the Structure and Dynamics of Mass-selected Biomolecular Ions CHIMIA biomolecular structure dynamics fluoresence ion spectroscopy mass spectrometry |
author_facet |
Prince Tiwari |
author_sort |
Prince Tiwari |
title |
Fluorescence-based Techniques to Study the Structure and Dynamics of Mass-selected Biomolecular Ions |
title_short |
Fluorescence-based Techniques to Study the Structure and Dynamics of Mass-selected Biomolecular Ions |
title_full |
Fluorescence-based Techniques to Study the Structure and Dynamics of Mass-selected Biomolecular Ions |
title_fullStr |
Fluorescence-based Techniques to Study the Structure and Dynamics of Mass-selected Biomolecular Ions |
title_full_unstemmed |
Fluorescence-based Techniques to Study the Structure and Dynamics of Mass-selected Biomolecular Ions |
title_sort |
fluorescence-based techniques to study the structure and dynamics of mass-selected biomolecular ions |
publisher |
Swiss Chemical Society |
series |
CHIMIA |
issn |
0009-4293 2673-2424 |
publishDate |
2021-04-01 |
description |
Laser-induced fluorescence studies on mass-selected biomolecules are a promising route to understand their properties in the gas phase and probe their intrinsic properties in a solvent-free environment. Fluorescence has been used to investigate the conformation and dynamics of gaseous biomolecular ions. With Förster Resonance Energy Transfer (FRET), it is now possible to obtain sensitive intramolecular distance information from large biomolecules, like proteins, with high chemical specificity. With growing interest and applications, gas-phase fluorescence measurements can shed greater light on the characteristics of proteins in the gas phase. Compared to the solution phase measurements, gas-phase fluorescence can also help understand the influence of solvent interactions on the protein structure and function. |
topic |
biomolecular structure dynamics fluoresence ion spectroscopy mass spectrometry |
url |
https://www.ingentaconnect.com/contentone/scs/chimia/2021/00000075/00000004/art00002 |
work_keys_str_mv |
AT princetiwari fluorescencebasedtechniquestostudythestructureanddynamicsofmassselectedbiomolecularions |
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1721457020907814912 |