Repair abilities of mouse autologous adipose-derived stem cells and ShakeGel™3D complex local injection with intrauterine adhesion by BMP7-Smad5 signaling pathway activation

Repair abilities of mouse autologous adipose-derived stem cells and ShakeGel™3D complex local injection with intrauterine adhesion by BMP7-Smad5 signaling pathway activation

Abstract Background The objective was to explore the therapeutic effect of autologous adipose-derived stem cells (ADSCs) combined with ShakeGel™3D transplantation to activate the BMP7-Smad5 signaling pathway to treat intrauterine adhesions (IUA). Methods Autologous ADSCs were isolated and then merge...

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Bibliographic Details
Main Authors:	Yun-xia Zhao, Shao-rong Chen, Qiao-yi Huang, Wei-can Chen, Tian Xia, Yan-chuan Shi, Hong-zhi Gao, Qi-yang Shi, Shu Lin
Format:	Article
Language:	English
Published:	BMC 2021-03-01
Series:	Stem Cell Research & Therapy
Subjects:	Autologous adipose-derived stem cells ShakeGel™3D Intrauterine adhesion BMP7-Smad5 signaling pathway
Online Access:	https://doi.org/10.1186/s13287-021-02258-0

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