cAMP-Inhibits Cytoplasmic Phospholipase A2 and Protects Neurons against Amyloid-β-Induced Synapse Damage
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate in Parkinson’s disease, also caused synapse d...
Main Authors: | Clive Bate, Alun Williams |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-09-01
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Series: | Biology |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-7737/4/3/591 |
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