Advances in Metal-Catalyzed Cross-Coupling Reactions of Halogenated Quinazolinones and Their Quinazoline Derivatives

Halogenated quinazolinones and quinazolines are versatile synthetic intermediates for the metal-catalyzed carbon–carbon bond formation reactions such as the Kumada, Stille, Negishi, Sonogashira, Suzuki-Miyaura and Heck cross-coupling reactions or carbon-heteroatom bond formation via the Buchwald-H...

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Main Authors:	Malose Jack Mphahlele, Marole Maria Maluleka
Format:	Article
Language:	English
Published:	MDPI AG 2014-10-01
Series:	Molecules
Subjects:	halogenoquinazolin-4-ones halogenoquinazolines cross-coupling reactions
Online Access:	http://www.mdpi.com/1420-3049/19/11/17435

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spelling	doaj-249c20cf82c143d3919930440bf63e152020-11-25T00:50:05ZengMDPI AGMolecules1420-30492014-10-011911174351746310.3390/molecules191117435molecules191117435Advances in Metal-Catalyzed Cross-Coupling Reactions of Halogenated Quinazolinones and Their Quinazoline DerivativesMalose Jack Mphahlele0Marole Maria Maluleka1Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, P.O. Box 392, Pretoria 0003, South AfricaDepartment of Chemistry, College of Science, Engineering and Technology, University of South Africa, P.O. Box 392, Pretoria 0003, South AfricaHalogenated quinazolinones and quinazolines are versatile synthetic intermediates for the metal-catalyzed carbon–carbon bond formation reactions such as the Kumada, Stille, Negishi, Sonogashira, Suzuki-Miyaura and Heck cross-coupling reactions or carbon-heteroatom bond formation via the Buchwald-Hartwig cross-coupling to yield novel polysubstituted derivatives. This review presents an overview of the application of these methods on halogenated quinazolin-4-ones and their quinazolines to generate novel polysubstituted derivatives.http://www.mdpi.com/1420-3049/19/11/17435halogenoquinazolin-4-oneshalogenoquinazolinescross-coupling reactions
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Malose Jack Mphahlele Marole Maria Maluleka
spellingShingle	Malose Jack Mphahlele Marole Maria Maluleka Advances in Metal-Catalyzed Cross-Coupling Reactions of Halogenated Quinazolinones and Their Quinazoline Derivatives Molecules halogenoquinazolin-4-ones halogenoquinazolines cross-coupling reactions
author_facet	Malose Jack Mphahlele Marole Maria Maluleka
author_sort	Malose Jack Mphahlele
title	Advances in Metal-Catalyzed Cross-Coupling Reactions of Halogenated Quinazolinones and Their Quinazoline Derivatives
title_short	Advances in Metal-Catalyzed Cross-Coupling Reactions of Halogenated Quinazolinones and Their Quinazoline Derivatives
title_full	Advances in Metal-Catalyzed Cross-Coupling Reactions of Halogenated Quinazolinones and Their Quinazoline Derivatives
title_fullStr	Advances in Metal-Catalyzed Cross-Coupling Reactions of Halogenated Quinazolinones and Their Quinazoline Derivatives
title_full_unstemmed	Advances in Metal-Catalyzed Cross-Coupling Reactions of Halogenated Quinazolinones and Their Quinazoline Derivatives
title_sort	advances in metal-catalyzed cross-coupling reactions of halogenated quinazolinones and their quinazoline derivatives
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2014-10-01
description	Halogenated quinazolinones and quinazolines are versatile synthetic intermediates for the metal-catalyzed carbon–carbon bond formation reactions such as the Kumada, Stille, Negishi, Sonogashira, Suzuki-Miyaura and Heck cross-coupling reactions or carbon-heteroatom bond formation via the Buchwald-Hartwig cross-coupling to yield novel polysubstituted derivatives. This review presents an overview of the application of these methods on halogenated quinazolin-4-ones and their quinazolines to generate novel polysubstituted derivatives.
topic	halogenoquinazolin-4-ones halogenoquinazolines cross-coupling reactions
url	http://www.mdpi.com/1420-3049/19/11/17435
work_keys_str_mv	AT malosejackmphahlele advancesinmetalcatalyzedcrosscouplingreactionsofhalogenatedquinazolinonesandtheirquinazolinederivatives AT marolemariamaluleka advancesinmetalcatalyzedcrosscouplingreactionsofhalogenatedquinazolinonesandtheirquinazolinederivatives
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Advances in Metal-Catalyzed Cross-Coupling Reactions of Halogenated Quinazolinones and Their Quinazoline Derivatives

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