Ube3a deficiency inhibits amyloid plaque formation in APPswe/PS1δE9 mouse model of Alzheimer’s disease

Ube3a deficiency inhibits amyloid plaque formation in APPswe/PS1δE9 mouse model of Alzheimer’s disease

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive decline in memory and cognitive function. Pathological hallmark of AD includes aberrant aggregation of amyloid beta (Aβ) peptide, which is produced upon sequential cleavage of amyloid precursor protein (APP) b...

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Bibliographic Details
Main Authors:	Brijesh Kumar Singh, Naman Vatsa, Vipendra Kumar, Shashi Shekhar, Ankit Sharma, Nihar Ranjan Jana
Format:	Article
Language:	English
Published:	Science Planet Inc. 2017-10-01
Series:	Canadian Journal of Biotechnology
Online Access:	https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue/cjb.2017-a163.pdf

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