Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation

Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation

Summary: Adrenergic stimulation of brown adipose tissue (BAT) induces acute and long-term responses. The acute adrenergic response activates thermogenesis by uncoupling oxidative phosphorylation and enabling increased substrate oxidation. Long-term, adrenergic signaling remodels BAT, inducing adapti...

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Bibliographic Details
Main Authors: Erin L. Brown, Bethany C. Hazen, Elodie Eury, Jean-Sébastien Wattez, Marin L. Gantner, Verena Albert, Sarah Chau, Manuel Sanchez-Alavez, Bruno Conti, Anastasia Kralli
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218300142

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