An effective "three-in-one" screening assay for testing drug and nanoparticle toxicity in human endothelial cells.

Evaluating nanoparticle (NP) toxicity in human cell systems is a fundamental requirement for future NP biomedical applications. In this study, we have designed a screening assay for assessing different types of cell death induced by NPs in human umbilical vein endothelial cell (HUVEC) culture. This...

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Bibliographic Details
Main Authors: Marcela Filipova, Oumsalama K Elhelu, Silvia H De Paoli, Zuzana Fremuntova, Tibor Mosko, Dusan Cmarko, Jan Simak, Karel Holada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6209339?pdf=render