GRIBCG: a software for selection of sgRNAs in the design of balancer chromosomes
Abstract Background Balancer chromosomes are tools used by fruit fly geneticists to prevent meiotic recombination. Recently, CRISPR/Cas9 genome editing has been shown capable of generating inversions similar to the chromosomal rearrangements present in balancer chromosomes. Extending the benefits of...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-03-01
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| Series: | BMC Bioinformatics |
| Online Access: | http://link.springer.com/article/10.1186/s12859-019-2712-x |